Expression of LINE-1 Retrotransposons in Human Breast Cancer
ARMED FORCES INST OF PATHOLOGY WASHINGTON DC
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Several diseases have been linked to the insertion of human LINE-1 retrotransposons LlHs into structural genes. Recently, the element has been shown to be expressed in a variety of adult and pediatric germ cell cancers, leading to speculation that LlHs-induced insertion mutation may play a role in the etiology of some neoplasias. Breast cancer, Retrotransposon, Gene expression, Immunohistochemistry, Reprint, RAD VI.
- Genetic Engineering and Molecular Biology
- Medicine and Medical Research