Accession Number:

ADA280345

Title:

Expression of LINE-1 Retrotransposons in Human Breast Cancer

Descriptive Note:

Corporate Author:

ARMED FORCES INST OF PATHOLOGY WASHINGTON DC

Report Date:

1994-05-01

Pagination or Media Count:

5.0

Abstract:

Several diseases have been linked to the insertion of human LINE-1 retrotransposons LlHs into structural genes. Recently, the element has been shown to be expressed in a variety of adult and pediatric germ cell cancers, leading to speculation that LlHs-induced insertion mutation may play a role in the etiology of some neoplasias. Breast cancer, Retrotransposon, Gene expression, Immunohistochemistry, Reprint, RAD VI.

Subject Categories:

  • Genetic Engineering and Molecular Biology
  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE