Acute Hepatitis E Infection During the 1988 Floods in Khartoum, Sudan
NAVAL MEDICAL RESEARCH INST BETHESDA MD
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Following catastrophic floods in August 1988, physicians in Khartoum and Omdurman, Sudan, observed an outbreak of acute hepatitis. During a period of 2 weeks in October 1988 we conducted a seroepidemiological study of icteric patients presenting to an acute-care clinic at the Omdurman Military Hospital. After informed consent was obtained, a standardized questionnaire was administered to each person and a venous blood sample was obtained. Acute and convalescent sera were tested for immunoglobulin Ig M and IgG antibody to hepatitis E virus anti-HEV using a Western blot assay. Specimens were also tested for IgM antibody to the hepatitis B core protein and IgM antibody to hepatitis A virus.
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