Accession Number:

ADA279534

Title:

Production of Anti-Ferret IgA Antibodies; and production of monoclonal antibodies

Descriptive Note:

Quarterly progress rept., no. 5, 1 Jan-31 Mar 1994

Corporate Author:

HAWAII BIOTECHNOLOGY GROUP INC AIEA

Personal Author(s):

Report Date:

1994-04-26

Pagination or Media Count:

5.0

Abstract:

A Production of anti-ferret IgA antibodies. Status Rabbit immunization completed. Immune serum collected. Currently cross-adsorbing serum with ferret IgG. Purification of lipopolysaccharide from Shigella and Campylobacter species. Status Preparation of Shigella LPS completed. Material delivered to Navy. Production of Campylobacter LPS on hold. Development of an enzyme immunoassay for the detection of enteroaggregative Escherichia coli heat- stable toxin. Status This portion of the project has been suspended. Production of monoclonal antibodies against strain-specific antigenic epitopes on amplylobacter coli flagella. Status have completed screening hybridomas from two fusions. Flagellin reactive MAbs produced no strain-specific MAbs identified. Preparing for third fusion.

Subject Categories:

  • Medicine and Medical Research
  • Pharmacology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE