Acute Radiation Sickness Amelioration Analysis
Technical rept. 20 Jul 1990-19 Jul 1993
SCIENCE APPLICATIONS INTERNATIONAL CORP MCLEAN VA
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Three tasks were conducted under the Acute Radiation Sickness Amelioration Analysis in support of the Defense Nuclear Agency DNA and NATO army Armaments Group NAAG Project Group 29 PG-29 on drugs for the prevention of radiation-induced nausea and vomiting 1 documents were collected and entered into a data base, 2 data reviews and analyses were performed, and 3 PG-29 and Triservice meetings involving anti-emetic drug development were supported and documented. Approximately 2000 documents were collected, with 1424 complete bibliographic citations entered into a WordPerfect 5.1 data base. Eight reviews and analyses addressing different aspects of the safety and efficacy of the candidate anti-emetic drugs ondansetron and granistron were prepared. Support was provided for seven international PG-29 meetings and two U.S. Triservice meetings in which the efforts of PG-29 were discussed. These tasks have enabled the DNA and PG-29 to make good progress toward the goal of recommending a serotonin type-3 5-HT3 receptor antagonist anti-emetic drug for use in military personnel.
- Computer Systems