Accession Number:

ADA279084

Title:

Acute Radiation Sickness Amelioration Analysis

Descriptive Note:

Technical rept. 20 Jul 1990-19 Jul 1993

Corporate Author:

SCIENCE APPLICATIONS INTERNATIONAL CORP MCLEAN VA

Report Date:

1994-05-01

Pagination or Media Count:

39.0

Abstract:

Three tasks were conducted under the Acute Radiation Sickness Amelioration Analysis in support of the Defense Nuclear Agency DNA and NATO army Armaments Group NAAG Project Group 29 PG-29 on drugs for the prevention of radiation-induced nausea and vomiting 1 documents were collected and entered into a data base, 2 data reviews and analyses were performed, and 3 PG-29 and Triservice meetings involving anti-emetic drug development were supported and documented. Approximately 2000 documents were collected, with 1424 complete bibliographic citations entered into a WordPerfect 5.1 data base. Eight reviews and analyses addressing different aspects of the safety and efficacy of the candidate anti-emetic drugs ondansetron and granistron were prepared. Support was provided for seven international PG-29 meetings and two U.S. Triservice meetings in which the efforts of PG-29 were discussed. These tasks have enabled the DNA and PG-29 to make good progress toward the goal of recommending a serotonin type-3 5-HT3 receptor antagonist anti-emetic drug for use in military personnel.

Subject Categories:

  • Radiobiology
  • Computer Systems

Distribution Statement:

APPROVED FOR PUBLIC RELEASE