Accession Number:

ADA276567

Title:

Combinatorial Ion Sensors

Descriptive Note:

Annual rept. 15 Feb 1993-14 Feb 1994

Corporate Author:

COLUMBIA UNIV NEW YORK DEPT OF CHEMISTRY

Personal Author(s):

Report Date:

1994-02-14

Pagination or Media Count:

3.0

Abstract:

The objective is to develop a massively parallel combinatorial method for preparing and screening ionophores which selectively bind group IIB and divalent transition metals. The accomplishments were During the past year, we have prepared for and begun preparation of an encoded combinatorial library of cyclen-based receptors and also validated a color-based assay for detecting certain metal-binding ligands. The latter study was designed as a positive control to show that good metal-binding polymer-supported ligands could be detected visually from a library of relatively poor ionophoric ligands.

Subject Categories:

  • Inorganic Chemistry
  • Polymer Chemistry
  • Computer Systems
  • Atomic and Molecular Physics and Spectroscopy

Distribution Statement:

APPROVED FOR PUBLIC RELEASE