Accession Number:

ADA276469

Title:

Lectin Enzyme Assay Detection of Viruses, Tissue Culture, and a Mycotoxin Simulant

Descriptive Note:

Technical rept. Feb 1982-Aug 1985

Corporate Author:

CHEMICAL RESEARCH DEVELOPMENT AND ENGINEERING CENTER ABERDEEN PROVING GROUND MD

Personal Author(s):

Report Date:

1988-09-01

Pagination or Media Count:

21.0

Abstract:

Nonspecific lectin detection of virus groups depends on the lectin binding with the specific virus protein polysaccharide. Prevot and Guesdon used wheat germ agglutinin WGA to detect rotavirus antigen in an erythro-lectin immunoassay. WGA has an avidity specificity for N-acetyl glucosamine and a lesser specificity for sialic acid. Delagneau, Perrin, and Atanasiu found that the following five different lectins had an affinity for rabies virus Phaseolus vulgaris PHA- red kidney bean agglutinin, Triticum vulgaris WGA- wheat germ agglutinin, Ricinus culinaris RCA-castor bean agglutinin, Lens culinaris LCA - lentil agglutinin, Concanavalia ensiformis Con A - jack bean agglutinin to a lesser degree

Subject Categories:

  • Medicine and Medical Research
  • Microbiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE