Effects of Pressure on Membrane-Associated Receptors and Effector Elements
Rept. for 1 Jun-30 Nov 1993
LOUISIANA STATE UNIV BATON ROUGE
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To identify the effects of moderate hydrostatic pressure on receptor and effector elements involved in transmembrane signal transduction, we examined the A1 adenosine receptor - inhibitory G protein G - adenylylcyclase signal transduction complex. Our experiments were designed to identify and define at the molecular level pressure effects on system components in isolation and on the entire functional complex.