The Influence of Multiple Host Contacts on the Acquisition and Transmission of Dengue-2 Virus
AIR FORCE INST OF TECH WRIGHT-PATTERSON AFB OH
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I tested assumptions of the hypothesis that multiple host contacts by Ae. aegypti contribute to dengue virus transmission, the hypothesis assumes multiple meals that combine a viremic meal with a meal from an immune host will not interfere with mosquito infection. I administered enemas, which simulated a second meal from an immune host, to Ae. aegypti that had fed 24 hours earlier from a drop of dengue-2 virus infected blood. Infection rates of the mosquitoes receiving immune sera 85 were significantly lower than the controls 92. Lower infection rates reduce the potential for virus transmission. In vitro transmission rates of the mosquitoes that become infected were not altered by the immune sera.
- Medicine and Medical Research