Accession Number:

ADA273581

Title:

Eradication of Herpesvirus simiae from a Rhesus Monkey Breeding Colony. B-virus Eradication in Breeding Rhesus

Descriptive Note:

Final rept. Nov 1987-Jan 1992

Corporate Author:

ARMSTRONG LAB BROOKS AFB TX OCCUPATIONAL AND ENVIRONMENTAL HEALTH DIRECTORATE

Report Date:

1992-10-01

Pagination or Media Count:

6.0

Abstract:

In the fall of 1987, the establishment of a Herpesvirus simiae B- virus negative rhesus monkey Macaca mulatta breeding colony was initiated at the Armstrong Laboratory. A serological testing program was used to categorize all monkeys into groups of either positive or negative to B-virus. Segregation of the groups allowed the creation of breeding harems that were exclusively serum positive or negative to B-virus while allowing maintenance of a similar level of infant production. Decreasing numbers of animals converted to a positive status during the first three followup serum tests for B-virus in the program. During 1990 an increase in the number of monkeys converting to positive status and the discovery of an indeterminate status demonstrated that the latency of B-virus in the rhesus may have the potential to defeat an eradication attempt not conscientiously pursued. Nonhuman primate, Rhesus, Macaca mulatta, Breeding colony, Herpesvirus simiae, Simian B virus, B-virus.

Subject Categories:

  • Microbiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE