Effect of Photoperiod on Blood Cholinesterase Activity and Melatonin Concentrations in Adult Cats
ARMY AEROMEDICAL RESEARCH LAB FORT RUCKER AL
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Activity of synaptically released acetylcholine Ach is terminated by the degradative enzyme acetylcholinesterase AChE, or true cholinesterase. There is a second class of cholinesterase found in living systems, pseudocholinesterase butyrylcholinesterase, BUChE which preferentially hydrolyzes higher choline esters. Some of our previous studies with cholinesterase inhibitors relate decrements in the visual evoked response VER to inhibition of AchE or BUChE. Initial decrements in the VER appear to be related to blood activity of cholinesterases. In addition to AchE inhibition, other neurochemical alterations have been reported after exposure of animals to organophosphate OP.
- Anatomy and Physiology