Accession Number:

ADA270015

Title:

Plasmodium Coatneyi Ring-Infected Erythrocyte Surface Antigens

Descriptive Note:

Corporate Author:

WALTER REED ARMY INST OF RESEARCH WASHINGTON DC

Report Date:

1993-01-01

Pagination or Media Count:

9.0

Abstract:

Plasmodium coatneyi produced ring-infected erythrocyte surface antigen RESA during infection of the rhesus monkey. This antigen was immunogenic and elicited an antibody response that was not persistent but was boosted by repeated infections in a manner similar to that seen in P. falciparum infections in humans. Preliminary data showed that the appearance and increasing titer of antibodies to P. coatneyi RESA-like antigen were associated with prolongation of intervals from innoculation to potency and with control of parasitemia.

Subject Categories:

  • Medicine and Medical Research
  • Microbiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE