Accession Number:

ADA265972

Title:

Role of Spatially Distributed Ion Channels in Single Neuron Computation

Descriptive Note:

Final rept. 1 Mar 1990-15 Dec 1992

Corporate Author:

WASHINGTON UNIV SEATTLE DEPT OF PHYSIOLOGY AND BIOPHYSICS

Personal Author(s):

Report Date:

1993-05-17

Pagination or Media Count:

5.0

Abstract:

Towards the overall goal of making an accurate mathematical model of a neocortical pyramidal neuron, 1 the electrical properties of Na and Ca2 channel subtypes were measured in sufficient detail to construct a quantitative empirical model, and 2 antibodies were raised against the a1 subunits of these channel subtypes in order to determine their spatial distribution and relative density using quantitative immunocytochemistry.... Ion channels, Sodium, Calcium, Electrophysiology, Immunocytochemistry

Subject Categories:

  • Atomic and Molecular Physics and Spectroscopy

Distribution Statement:

APPROVED FOR PUBLIC RELEASE