Accession Number:

ADA265568

Title:

Experimental Vector Incompetence of a Soft Tick, Ornithodoros sonrai (Acari: Argasidae), for Crimean-Congo Hemorrhagic Fever Virus

Descriptive Note:

Corporate Author:

ARMY MEDICAL RESEARCH INST OF INFECTIOUS DISEASES FORT DETRICK MD

Report Date:

1993-01-01

Pagination or Media Count:

4.0

Abstract:

Adults and nymphs of a soft tick, Ornithodoros sonrai Sautet and Witkowski, were allowed to feed on suckling mice that had been experimentally infected with Crimean-Congo hemorrhagic fever CCHF virus IbAr 10200 strain. The mean viral titer of mouse blood at the time of tick feeding was 103.2 plaque-forming units PFU per ml. Samples of ticks were assayed on 12 occasions between days 0 and 31 after the viremic blood meal. Mean CCHF viral titers were 102.1 PFU per tick immediately after the viremic meal but declined to 101.2 PFU per tick after 2 d, and no virus was detected beyond 8 d. The percentage of ticks with detectable virus was 92 2224 immediately after the viremic meal, but then declined to 20 210 after 4 dand to 0 044 after 11 or more days. Ticks were allowed to feed on sets of three naive sickling mice on days 0, 2, 5, 8, 11, 14, 21, and 28 after the viremic blood meal, but CCHF viral transmission did not occur. Similarly, no transovarial transmission of virus from CCHF virus- exposed O. sonrai to their progeny was observed. These results strongly indicate that O. sonrai is not a vector of CCHF virus

Subject Categories:

  • Medicine and Medical Research
  • Microbiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE