Accession Number:

ADA265528

Title:

Amperometric Biosensors Based on 3-Dimensional Hydrogel-Forming Epoxy Networks

Descriptive Note:

Technical rept. Oct 1992-May 1993

Corporate Author:

TEXAS UNIV AT AUSTIN DEPT OF CHEMICAL ENGINEERING

Report Date:

1993-05-24

Pagination or Media Count:

12.0

Abstract:

Proteins and glycoproteins of enzymes behave with respect to electron transport, but not ion transport, as good electrical insulators. We have shown that these insulators can be made sufficiently electron conducting to allow the flow of a current between reaction centers of redox enzymes and electrodes equaling or exceeding the current associated with the turnover of the enzymes. In order for such a current to flow it is necessary to introduce into the enzyme proteins of glycoproteins fast electron relaying centers, so as to reduce the electron transfer distances.

Subject Categories:

  • Biochemistry
  • Organic Chemistry
  • Physical Chemistry

Distribution Statement:

APPROVED FOR PUBLIC RELEASE