The Effect of Alkyl Substituents on the Macrocycle Ring on Enantiomeric Recognition by Chiral Pyridino-18-Crown-6 for 1-Naphthylethylamine
BRIGHAM YOUNG UNIV PROVO UT DEPT OF CHEMISTRY
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This paper discusses the effect that various dialkyl substitutents on chiral pyridino-18-crown-6 ligands have on the molecular recognition of these ligands for the R and S-alpha-1-naphthylethyl ammonium perchlorate. We have systematically synthesized the necessary chiral pyridino-18-crown-6 macrocycles and determined the extent of molecular recognition by titration calorimetry. This paper also discusses possible mechanisms of recognition.
- Organic Chemistry
- Physical Chemistry
- Atomic and Molecular Physics and Spectroscopy