Iron Malabsorption in a Patient With Large Cell Lymphoma Involving the Duodenum
WALTER REED ARMY INST OF RESEARCH WASHINGTON DC
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Antemortem diagnosis of gastrointestinal involvement by non-Hodgkins lymphoma occurs in approximately 10 of cause. Malabsorption secondary to small bowel involvement by lymphoma in distinctly uncommon and iron deficiency in rarely the sole manifestation of malabsorption. We report a patient with the unusual feature of iron deficiency anemia compounded by selective malabsorption of iron because of occult lymphomatous diffuse large cell involvement of the small intestine. Both upper gastrointestinal series with small bowel follow- through and CT scan demonstrated lymphomatous involvement of the duodenum and proximal jejunum by a retroperitoneal mass. An oral iron loading absorption test was consistent with malabsorption of iron. After two cycles of systemic chemotherapy, the retroperitoneal mass had resolved and the iron loading test normalized.
- Medicine and Medical Research