Alterations in Morphology and ERG Spectral Sensitivity After Near IR (1064 nm) multiple Parafoveal Q-Switched Laser Exposure.
LETTERMAN ARMY INST OF RESEARCH PRESIDIO OF SAN FRANCISCO CA
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In this investigation we examined the effect of near-infrared intense macular laser exposure on the non-human primate focal ERG spectral sensitivity function. Five cynomologous monkeys were exposed to two parafoveal Q-switched Neodymium 1064 nm lager pulses at approximately 4 millijoules Total Interocular Energy TIE. Exposures varied in degree of overlap through the superior portion of the fovea. Focal ERG spectral sensitivity was measured in the foveal region using a synchronous detection technique. Alteration in the long wavelength region of the focal ERG spectral sensitivity function was observed in all animals. This alteration could indicate a dominant presence of the long wavelength primate cone system. The dominance may be the result of neural disinhibitory effects of damaged photoreceptors and the complications of retinal fibrosis on normal receptor activity and orientation as well as normal retinal receptor reparative functions. Spectral sensitivity, fovea, retinal fibrosis, reparative functions, photoreceptors.
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