Accession Number:

ADA256420

Title:

Synthetic Catalysts that Hydrolyze Phosphate and Carboxylate Esters

Descriptive Note:

Rept. no. 11 (Final) Mar 1991-Feb 1992

Corporate Author:

OHIO STATE UNIV COLUMBUS DEPT OF CHEMISTRY

Personal Author(s):

Report Date:

1992-09-18

Pagination or Media Count:

27.0

Abstract:

We are look for reaction types that simultaneously 1 provide for the reaction of acyl and phosphoryl groups under non-forcing conditions 2 suggest ways for elaboration into catalytic cycles with turnover behavior and, 3 survive translation onto binding moieties. To date, we have focussed on artificial metalloenzymes derived from CoIII and CuII coordination complexes with cyclodextrins, preassociating alpha-nucleophiles, and binuclear metal ion complexes.

Subject Categories:

  • Industrial Chemistry and Chemical Processing
  • Inorganic Chemistry
  • Radiation and Nuclear Chemistry

Distribution Statement:

APPROVED FOR PUBLIC RELEASE