HTLV-I Seroconversion Study.
Annual rept. (Final) 15 Nov 87-30 Sep 91,
NAVAL HEALTH RESEARCH CENTER SAN DIEGO CA
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A study site was established on Okinawa, a hyperendemic area for the human T-cell leukemia virus-I HTLV-1, for the purpose of studying the risk of HTLV-I transmission to the active duty personnel stationed there. Research activities completed include an HTLV-I seroprevalence survey and a prospective study for HTLV seroconversion. A cross-sectional HTLV serologic survey was conducted among 5,255 active duty U.S. Marines on permanent tour stationed in Okinawa, Japan to search for risk factors of seropositivity. Participants were primarily young, Caucasian males. Three 0.06 were confirmed positive for HTLV by western blot WB analysis, showing reactivity for core and envelope. All 3 seropositive cases have a history of prolonged sexual contact with Okinawan women, and two of the three are married to infected Okinawan RA 1, Seroconversion, Epidemiology
- Medicine and Medical Research