Experimental Research Into High Barometric Oxygen Prevention of Guinea Pig Hearing Loss,
FOREIGN AEROSPACE SCIENCE AND TECHNOLOGY CENTER WRIGHT-PATTERSON AFB OH
Pagination or Media Count:
Two groups of guinea pigs were exposed to an acoustical field of 125 dBSPL one kilohertz for three hours. One of these groups breathed high barometric oxygen at two atmospheres for three times prior to exposure and on 21 continuous days following exposure. They breathed this pure oxygen for one half hour each time. The other group was control and was not given pure oxygen. The indexes used to judge the results we induced potential hearing threshold of the hearing regions of the cerebral cortex and cochlea pathology. After exposure to sound, the average hearing loss of the high barometric oxygen group was 35 to 50 dB. That of the control group was 60 to 70 dB P0.01. The average total length of cochlear damage and the length of serious damage of the high barometric oxygen group were 80 microns and 34 microns while that of the control group was 267 and 210 microns respectively P0.01. The results indicate that high barometric oxygen acts to prevent and cure hearing loss.
- Anatomy and Physiology