Purification of the Alpha Glycerophosphate Oxidase From Trypanosomes.
Annual rept. 3 Feb 1986-31 Dec 1989 (Final),
MEHARRY MEDICAL COLL NASHVILLE TN
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The research problem we have been investigating is the purification of the glycerphosphate oxidase from the terminal oxidase in bloodstream trypanosomes. African trypanosomiasis remains one of the major diseases in the world today, affecting both man and animals. In addition, it remains on the list of the major health problems facing mankind today, which includes AIDS, malaria, cancer and heart disease. The land mass of Africa, south of the Sahara, over which tsetse flies are distributed and is thus virtually devoid of cattle and is estimated to be about 4 million square miles. It has been estimated that if this area could be used, at least 125 million cattle could be raised, more than doubling the present cattle population in Africa.