Hemorrhagic Fever With Renal Syndrome (Korean Hemorrhagic Fever).
Annual rept. (Final) 10 Feb 1986-9 Oct 1991,
KOREA UNIV SEOUL COLL OF MEDICINE
Pagination or Media Count:
World-wide, about 200,000 people are hospitalized with Hemorrhagic fever with renal syndrome HFRS 3-10 fatality each year. The etiologic agents of HFRS are Hantaan, Seoul and Puumala viruses of the genus Hantavirus, family Bunyaviridae. A severe form of HFRS, caused by Hantaan virus, occurs in Asia and eastern parts of Europe, a moderate form, caused by Seoul and Seoul- like virus, occurs in Asia, and a mild form, caused by Puumala virus, occurs in Europe. The reservoirs of hantaviruses are rodents and small mammals. Geographical distribution of hantaviruses and-surveillance of HFRS are important for prevention of this highly fatal disease. Little is known about the pathogenesis of HFRS. It is also important to investigate antigenic differences of hantaviruses isolated from non-endemic areas of the world because HFRS patients have never been documented in many areas despite the finding of positive man and rodents there.
- Medicine and Medical Research