The Influence of Antibodies to Selected Mosquito Immunogens on Mosquitoes Following Ingestion of Blood from an Immune Vertebrate Host.
Final rept. 1 Nov 89-30 Sep 91,
OHIO UNIV ATHENS
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Our objective in this pilot project has been to examine the effects of mouse antibodies directed against concealed antigens on the life processes of the mosquito Aedes aegypti. We immunized mice with mosquito antigens prepared from sugar-fed and blood-fed mosquitoes as follows heads and thoraces, abdomens, and dissected midguts. After determining the immune status, using an ELISA, of the immunized mice, we allowed samples of mosquitoes to obtain blood meals and then determined survivorship, fecundity and egg viability our results did not indicate a deleterious effect of antibodies from an immune mouse on mosquito survivorship, the number of eggs deposited fecundity, or the viability of eggs deposited. Mosquitoes Concealed antigens Mosquito immunogens Antibodies to mosquito antigens RA 1.
- Anatomy and Physiology