Accession Number:

ADA254771

Title:

Development of Rules for Folding of Biotechnology Produced Protein.

Descriptive Note:

Final rept. 1 Feb-31 Jul 92,

Corporate Author:

BIOELASTICS RESEARCH LTD BIRMINGHAM AL

Personal Author(s):

Report Date:

1992-07-01

Pagination or Media Count:

32.0

Abstract:

Two fundamental contributions have been made in Phase I. The target of a Glu pKa shift of up to 3 pH units was exceeded and a series of solutes within the new Tt paradigm can be readily defined as to whether and with what efficacy they enhance or disrupt hydrophobic folding and assembly in proteins.

Subject Categories:

  • Radiobiology
  • Protective Equipment

Distribution Statement:

APPROVED FOR PUBLIC RELEASE