Accession Number:

ADA254744

Title:

Studies of Infection and Dissemination of Rift Valley Fever Virus in Mosquitoes.

Descriptive Note:

Final rept. 15 May 89-14 Sep 91,

Corporate Author:

OHIO UNIV ATHENS

Personal Author(s):

Report Date:

1991-10-15

Pagination or Media Count:

182.0

Abstract:

During the past two years, we have carried out the following studiesl Ultrastructural study of Rift Valley fever RVF virions in the cardia. 2 Immunocytochemical studies of the salivary glands and other tissues in Anopheles sp. which had been shown to be non-transmitters when intrathoracically-infected as adults, but transmitters when infected as immatures. 3 Immunocytochemical study of Ockelbo virus in Culex pipiens. 4 Ultrastructural examination of various tissues for RVF virus in hemocoelically- infected Cx. pipiens. 5 Development of an immunogold procedure for in situ labelling of RVF virions in electron microscopic preps. 6 Worked toward the identification and isolation of the mosquito cell surface receptor molecule for RVF virus. 7 Developed and presented a pre-meeting workshop, Mosquito Histology, Ultrastructure, and Methods for In situ Localization of Viruses, held in conjunction with the annual meeting of the American Society of Tropical Medicine and Hygiene. 8 Made progress in the development of a monograph on mosquito histology and ultrastructure. Rift Valley fever, mosquitos, infection, dissemination, mosquito tissue tropisms, infection and escape barriers , electron microscopy, immunogold-labelling immunocytochemistry, cell surface receptor, Ockelbo virus,

Subject Categories:

  • Biology
  • Ecology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE