Cold Stress and Delayed Matching-to-Sample: The Effects of Tyrosine
Technical rept. Oct 1991-Sep 1992,
NAVAL MEDICAL RESEARCH INST BETHESDA MD
Pagination or Media Count:
Military personnel can experience memory deficits while working in cold environments. The inability to recall standard operating procedures during cold exposure could jeopardize personal safety and military operations. It is possible that cold-induced memory deficits could, in part, be ameliorated through pharmacological intervention. To test this assumption, a delayed matching-to-sample task was used to assess working memory in rats exposed to 2 deg C or 22 deg C following tyrosine 50-200 pigkg or saline administration. overall matching accuracy was lower at 2 deg C than at 22 0 C. Tyrosine improved overall accuracy at 2 deg C relative to saline. The data support the hypothesis that tyrosine attenuates catecholamine depletion during cold exposure, reducing cold stress-induced performance deficits. Tyrosine, Delayed Matching-to-Sample, Rats, Short-term Memory.
- Stress Physiology