Accession Number:
ADA254091
Title:
Development of Methods for Detection of Lipid Peroxidation Products in Human Tissues Generated by Environmental Toxins.
Descriptive Note:
Annual rept. 1 Jul 91-30 Jun 92,
Corporate Author:
MONTANA STATE UNIV BOZEMAN DEPT OF CHEMISTRY
Personal Author(s):
Report Date:
1992-06-30
Pagination or Media Count:
4.0
Abstract:
Research to date has resulted in the synthesis of isotope labelled 9- oxononanoate and the development of generic methods for the introduction of a variety of isotopic labels in the 4-hydroxyalkenals. Additional studies demonstrated that 4-hydroxyalkenals could be released from protein sulfhydryl groups. Future studies will investigate whether 4-hyroxynonenal binds to the sulfhydral groups on human rhodopsin interfering with the visual transduction process.
Subject Categories:
- Biology