Neostriatal Neuronal Activity and Behavior
Final rept. 1 Mar 1990-28 Feb 1992
TEXAS UNIV HEALTH SCIENCE CENTER AT DALLAS DEPT OF CELL BIOLOGY AND ANATOMY
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The second year of the project allowed major tasks to be completed in the evolution of the advanced technology required for this project. A continual interchange of concepts and technology was made possible by the coordination of the three projects of the University Initiative Program at Hahnemann University Dr John Chapin and at Bowman Gray Medical School Dr Samual A. Deadwyler. The goal was to evolve a system for acquisition of a large ensemble of neuron spike trains from connected brain regions in awake behaving rats. Summary Overall, the three projects have created a foundation of new methodology to promote the next decade of research on large-scale recording of ensemble neuron spike trains. We intend to apply these capabilities to studies of neural circuit models of cognition and long term responses to stress. The experimental aims of the project will be considered exclusively in the third year.
- Medicine and Medical Research