Accession Number:

ADA247089

Title:

Intracellular Membrane and Synaptic Properties in Medial Preoptic Slices Containing the Sexually Dimorphic Nucleus of the Rat

Descriptive Note:

Corporate Author:

AIR FORCE OFFICE OF SCIENTIFIC RESEARCH ARLINGTON VA BIOMIMETICS/BIOMATERIALS AND BIOINTERFACIAL SCIENCES

Personal Author(s):

• Hoffman, Neil W.
• Kim, Yang I.
• Gorski, Roger A.
• Dudek, F. E.

Report Date:

1992-01-01

Pagination or Media Count:

44.0

Abstract:

Passive and active electrophysiological properties of neurons n46 in the medial preoptic area MPOA were studied in hypothalamic slices from rats primarily males. This investigation evaluated whether the MPOA contains a heterogeneous population of cell types, defined on the basis of electrophysical properties such as low-threshold Ca2 spikes LTS and current-voltage I-V relations. Evoked and spontaneous synaptic potentials were also studied in these neurons. Electrical properties were compared between neurons in the sexually dimorphic nucleus of the preoptic area SDN-POA with those situated in other parts of the MPOA. Biocytin-injected neurons n-24 were found in the SDN-POA, as well as other parts of the medial preoptic nucleus and MPOA. Stained neurons had 1 or 2 primary dendrites 46 of stained cells or had multipolar dendritic arrays 54 of cells dendrites were aspiny or sparsely spiny and displayed limited branching. Morphologically definable cell types were not specific to medial preoptic subdivisions.

Descriptors:

• *CELLS
• RATS
• PASSIVE SYSTEMS
• ELECTRICAL PROPERTIES
• POPULATION
• HETEROGENEITY
• NERVE CELLS
• MEMBRANES
• MALES
• CELLS(BIOLOGY)
• SYNAPSE
• DENDRITIC STRUCTURE
• ELECTROPHYSIOLOGY

Subject Categories:

• Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE