Effects of Pressure on Lipid Lateral Distribution in Membranes
Final rept. 1 Jul 1988-30 Jun 1991,
MEHARRY MEDICAL COLL NASHVILLE TN
Pagination or Media Count:
The goals of this research are to develop a general method describing the relationship between the photophysical model and the fluorescence parameter, to use this general method to evaluate the adequacy of the Birks model in describing pyrene fluorescence, to use this general method to derive a new model which can satisfactorily describe pyrene fluorescence in membrane systems, to use the new model to determine the lateral distribution of pyrene-labeled phosphatidylcholine in membranes, to determine the lateral distribution of pyrene labeled lipids in membranes at high pressures, and to study other membrane phenomena at high pressures.
- Genetic Engineering and Molecular Biology