A Study of Neuronal Properties, Synaptic Plasticity and Network Interactions Using a Computer Reconstituted Neuronal Network Derived from Fundamental Biophysical Principles
BAYLOR COLL OF MEDICINE HOUSTON TX
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A standalone executable computer program of the neural simulator MacNeuron is developed on the Macintosh IIci and Quadra computers. Two versions are available one runs on the Macintosh II series computer with the math coprocessor installed, the other runs without the math coprocessor. The version with the math coprocessor executes faster than the one without the coprocessor. The current version version 0.3 release allows users to build a compartmental neuron, simulate the generation of action potentials and record any variables for graphical display. The variables include voltage, time and ionic concentration, etc. Each of these variables can be plotted on the graphical charts. A Tutorial Manual and a Users Guide Manual are written describing the simulator, its run-time environment and a guide to use the neural simulator program. The current version of MacNeuron implemented the numerical algorithms for driving the neural simulator. It also included the plotting routines for displaying the simulation results. The current version uses a window-based user- interface for building a network of neuron.
- Computer Programming and Software