Molecular Recognition in Gels, Monolayers, and Solids
HARVARD UNIV CAMBRIDGE MA DEPT OF CHEMISTRY
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This paper describes work in four areaaffinity electrophoresis of carbonic anhydrase in cross-linked polyacrylamide-derived gels containing immobilized derivatives of aryl sulfonamides inhibition of the hemagglutination of erythrocytes induced by influenza virus using water-soluble polyacrylamides bearing sialic acid groups the application of self-assembled monolayers SAMs of alkyl thiolates on gold to the study of protein adsorption on organic surfaces and the use of networks of hydrogen bonds to generate new classes of non-covalently assembled organic materials, both in solution and in crystals. This paper summarizes research in two areas of molecular recognitionaffinity polymers and molecular self assembly. We illustrate these areas by examples drawn from affinity gel electrophoresis, soluble synthetic macromolecular inhibitors of binding of influenza virus to erythrocytes protein adsorption on self assembled monolayers and self assembling hydrogen bonded molecular aggregates.
- Atomic and Molecular Physics and Spectroscopy