Investigation of Crimean-Congo Hemorrhagic Fever and Hemorrhagic Fever with Renal Syndrome in Greece
Final rept.15 Apr 87-15 Jun 90,
ARISTOTLE UNIV OF THESSALONIKI (GREECE) SCHOOL OF MEDICINE
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During a 3 year and 2 month period, from April 1987 to June 1990, 3, 067 human sere were tested for antibody to Hantaan and C-CHF viruses. The overall antibody prevalence rate was found to be 3,0 and 1,8 respectively. Animal serosurveys were conducted for antibody to C-CHF virus goats and sheep and for antibody to Hantaan virus small mammals. The overall antibody prevalence rate was found 3.8 and 2,8 in goats and sheep respectively. High antibody titers to Hantaan virus were detected only in Apodemus flavicollis sera suggesting that Ap. flavicollis is the possible host of the virus. A Hantavirus was isolated from a severely MFRS ill patient Serological comparison of the isolated virus to other Hantaviruses established it as a member of this group. Twenty HFRS cases have been serologically diagnosed. The disease was a severe form of HFRS with a mortality rate 15. For C-CHF blood samples were obtained from patients with disease resembling C-CHF 60 patients and from patients with other diseases. None of the patients was found to be infected with C-CHF virus. During May 1990, an inapparent C-CHF infection was serologically diagnosed.
- Medicine and Medical Research