Accession Number:

ADA239259

Title:

Characterization of Allergen Exposure in Homes

Descriptive Note:

Master's thesis,

Corporate Author:

AIR FORCE INST OF TECH WRIGHT-PATTERSON AFB OH

Personal Author(s):

Report Date:

1991-01-17

Pagination or Media Count:

134.0

Abstract:

Environmental sampling for allergen quantification is a relatively new field of endeavor. Current evaluations focus on surface sampling with vacuum devices using a variety of collection filters. In the allergy field, results have conventionally been reported in terms of a mass of antigen per a mass of total dust which varies in definition between analytical laboratories. Many of the sample protocols encourage composite sampling of many potential allergen sources to characterize an entire house. Allergen levels were measured in 41 surface samples, and units of surface concentration of mass of antigen per total sieved dust, mass of antigen per unit area, and mass of antigen per unit area times sample collection time were compared. For dust mite antigen Der f l there was low correlation between units of surface concentration. Concentration. Correlation between units for cat antigen Fel d l was strong. However, the more conventional unit of mass of antigen per unit area is demonstrated to be a more meaningful measure of reservoir potency. The impact of collection time and the appropriate way to incorporate it into measurements requires further study. This study shows that there is a significant difference between antigen content of various reservoir, such as carpets, sofas or chairs, and mattresses.

Subject Categories:

  • Medicine and Medical Research
  • Stress Physiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE