Accession Number:

ADA238405

Title:

Further Evaluation of a Mutagen-Attenuated Rift Valley Fever Vaccine in Sheep

Descriptive Note:

Corporate Author:

ARMY MEDICAL RESEARCH INST OF INFECTIOUS DISEASES FORT DETRICK MD

Personal Author(s):

• Morrill, J. C.
• Carpenter, L.
• Taylor, D.
• Ramsburg, H. H.
• Quance, J.
• Peters, C. J.

Report Date:

1991-01-01

Pagination or Media Count:

7.0

Abstract:

The outbreak of Rift Valley fever RVP in Egypt in 1977 was the first reported occurrence of Rift Valley fever virus RVFV outside sub-Saharan Africa. This epidemic emphasized the role of RVFV as a significant human pathogen and established the virus as a potential worldwide threat to human and livestock populations. Concern over further dissemination of the virus has prompted efforts to develop improved vaccines, as available formalin-inactivated and live-attenuated vaccines have disadvantages or practical limitations to their widespread use.

Descriptors:

• *SHEEP
• RIFT VALLEY FEVER VIRUS
• SUBSAHARAN AFRICA
• EGYPT
• THREATS
• DISTRIBUTION
• HUMANS
• POPULATION
• RIFT VALLEY FEVER
• VIRUSES
• PATHOGENESIS
• VACCINES
• LIVESTOCK
• REPRINTS
• GLOBAL

Subject Categories:

• Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE