Accession Number:

ADA238236

Title:

Chemotherapy and Drug Targeting in the Treatment of Leishmaniasis

Descriptive Note:

Annual rept. 15 May 90-14 May 91,

Corporate Author:

MASSACHUSETTS UNIV AMHERST

Personal Author(s):

Report Date:

1991-05-29

Pagination or Media Count:

45.0

Abstract:

Leishmaniasis, a disease caused by protozoan parasites of the Lesihsmania spp., is one of the major public health problems currently affecting humanity. Therapeutic agents for this disease is either ineffective or toxic. The purpose of this work is to aid in the development of an effective, non-toxic treatment for leishmaniasis. The objective of this research was to isolate and characterize unique leishmanial enzymes DNA polymerase and S- adenosylsynthetase for the purpose of chemotherapeutic exploitation.

Subject Categories:

  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE