Accession Number:

ADA238232

Title:

Transformation and Precipitation of Toxic Metals by 'Pseudomonas maltophilia'

Descriptive Note:

Annual technical rept. 1 May 90-30 Apr 91,

Corporate Author:

MEHARRY MEDICAL COLL NASHVILLE TN

Personal Author(s):

Report Date:

1991-05-31

Pagination or Media Count:

6.0

Abstract:

The aims of this research are to study each of the various molecular mechanisms whereby toxic metal cations and oxyanions are chemically transformed by Pseudomonas maltophilia strain OR-02. The research effort for the current year has focused on the microbial-dependent transformations of mercury, selenium, tellurium, chromium and lead. The NADPH-dependent reduction of HgII was catalyzed by an inducible mercuric reductase. The reduction of selenite and tellurite to their insoluble elemental forms was mediated by an intracellular glutathione reductase that utilized the spontaneously-formed bisgluthathio SeII or bisgluthathioTeII, respectively, as pseudosubstrates.

Subject Categories:

  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE