Accession Number:

ADA238188

Title:

Comparison of Radiofrequency Energy and Warmwater Thawing of Cryopreserved Red Blood Cells.

Descriptive Note:

Final rept.,

Corporate Author:

NAVAL AEROSPACE MEDICAL RESEARCH LAB PENSACOLA FL

Personal Author(s):

Report Date:

1990-12-31

Pagination or Media Count:

11.0

Abstract:

Units of cryopreserved packed red blood cells pRBCs were thawed either with warm water or with radiofrequency RF energy at 27.12 MHz and applied with a helical coil system. Cell metabolism, membrane integrity, and hematological parameters were used to assess postthaw cell viability. Results showed that a small amount of RF-induced cell damage due to localized overheating could not be eliminated, but there were no significant differences in the viability comparisons between groups. We concluded that the RF thawing of pRBCs produced no deleterious effects per se, but secondary heat damage prevented this method from being considered a practical modality given the presently available tools.

Subject Categories:

  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE