Accession Number:

ADA238069

Title:

Comparison of the Systemic and Microvascular Responses to Uncontrolled Hemorrhage in Anesthetized Rabbits

Descriptive Note:

Institute rept. 1988-1990,

Corporate Author:

LETTERMAN ARMY INST OF RESEARCH PRESIDIO OF SAN FRANCISCO CA

Report Date:

1991-04-01

Pagination or Media Count:

32.0

Abstract:

We studied the systemic and microvascular responses to moderate, uncontrolled aortic or vena caval hemorrhage in skeletal muscle. Both systemic arterial pressure and systemic hematocrit fell following hemorrhage. Arterial pressure recovered moderately by 30 minute post-hemorrhage. The drop in hematocrit following hemorrhage was due to translocation of interstitial and intracellular water into the vascular compartment ie., transcapillary refill. This change in hematocrit was similar following both types of hemorrhage. Transverse pre-terminal and terminal arterioles in the tenuissimus skeletal muscle of the rabbit constricted somewhat, however, the greatest constriction was in the terminal arterioles.

Subject Categories:

  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE