A Synthetic P-Nitrophenyl Esterase with Remarkable Substrate Selectivity
INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS DEPT OF CHEMISTRY
Pagination or Media Count:
A new linear polymer, poly1,1,3,3,-tetramethyl-7--4 pyridinyl-7- aza-2-oxa-1,3-disiladecane, 4, recently prepared and characterized in our laboratory, has been evaluated as a catalyst for hydrolysis of p-nitrophenyl esters. This synthetic material not only exhibits high levels of catalytic efficiency and conforms to the Michaelis-Menten model, but it also demonstrates enzyme-like specificity for esters derived from acids of moderate chain length with p-nitrophenyl tetradecanoate C14 the optimum substrate.
- Organic Chemistry