Inhalation Toxicology of Red and Violet Dye Mixtures, Chamber Concentration and Particle Size Distribution Report
Rept. for 1 Jan-21 Dec 1990
HEALTH EFFECTS RESEARCH LAB RESEARCH TRIANGLE PARK NC
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An inhalation exposure facility was developed at the U.S. Environmental Protection Agency, Research Triangle Park, NC, to conduct inhalation exposures of rodents and guinea pigs to dye mixtures used by the U.S. Army in the manufacture of smoke munitions. Initially, an evaluation of the prototype chamber aerosol homogeneity was conducted to determine the uniformity and reproducibility of the concentration and particle size of dye aerosol throughout the breathing zone of the test animalsDavies, et al. The red grenade mixture was formulated by combining the anthraquinone dye Disperse Red 11 DR11 and the azo dye Solvent Red 1 SR1 the violet grenade mixture was formulated from DR11 and Disperse Blue 3 DB3, another anthraquinone dye. The three dyes, DR11, SR1, and DB3, were chemically analyzed for purity and optically examined for size and shape. All pure dyes appeared to be stable at room temperature except DB3, which decomposes if not stored at 4C. The particle size ranges varied for each pure dye and structures were either amorphousazo dye or crystallineanthraquinone dyes.