Chemotherapy and Drug Targeting in the Treatment of Leishmaniasis
Annual rept. 15 May 1988-14 May 1989
MASSACHUSETTS UNIV AMHERST
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Leishmaniasis, a disease caused by protozoan parasites of the Leishmania spp., is one of the major public health problems currently affecting humanity. Therapeutic agents for this disease is either ineffective or toxic. The purpose of this work is to aid in the development of an effective, non-toxic treatment for leishmaniasis. The objectives of this research were the following 1 To develop a reliable in vitro method for measuring the potential toxicity of promising anti-leismanial drugs on human T4 lymphocytes. 2 To determine if the toxicities of these drugs on T4 cells could be reversed by the addition of nutritional supplements.
- Medicine and Medical Research