Accession Number:

ADA237229

Title:

Surface-Bound Membrane-Mimetic Assemblies: Electrostatic Attributes of Integral Membrane Proteins

Descriptive Note:

Final rept. Nov 87-Mar 91,

Corporate Author:

TSI MASON RESEARCH INST WORCESTER MA BIOCHEMISTRY DEPT

Personal Author(s):

Report Date:

1991-06-03

Pagination or Media Count:

4.0

Abstract:

The objective of this project was to develop a system for investigating stimulus-induced displacements of charges associated with integral membrane proteins. A technology was developed for incorporating membrane receptor proteins into matrices that mimic a natural lipid bilayer but which are bound to the surface of solid electrode materials. The focus of the investigation was on the photoreceptor protein, rhodopsin, as a model for a broad class of membrane receptor proteins.

Subject Categories:

  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE