Accession Number:

ADA237189

Title:

Preliminary Program Annual Conference on Shock (13th) Held in Tamarron, Durango, Colorado on 8-11 June 1990

Descriptive Note:

Corporate Author:

WILEY (JOHN) AND SONS INC NEW YORK

Personal Author(s):

Report Date:

1990-01-01

Pagination or Media Count:

113.0

Abstract:

We studied the therapeutic effects of continuously infused N- acetylcysteine, an O2 radical scavenger N, n6, and terbutaline, a beta2 agonist T, n6, versus dextrose controls C, N6 on hemodynamics and regional albumin extravasation in porcine septic shock. After instrumentation, injection of Tc-labeled red blood cells, and baseline measurements, pigs received a 90 min infusion of 11 or - 9 x 10 kg-1 live Escherichia coli bacteria. Thereafter, therapy was started, and 131I human serum albumin was injected. Images were obtained hourly using a gammacamera and a computer until 5 hours after baseline. Regions of interest were drawn in the Tc images, yielding regional ITc radioactivity ratios, with blood samples as reference.

Subject Categories:

  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE