Accession Number:

ADA235224

Title:

Effects of Ingestion of Zinc Naphthenate on the Reproduction Function of Rats. Phase 5

Descriptive Note:

Study rept. Jan 1987-Feb 1988

Corporate Author:

ARMY ENVIRONMENTAL HYGIENE AGENCY ABERDEEN PROVING GROUND MD

Personal Author(s):

• Michie, Mark W.
• Angerhofer, Richard A.
• Barlow, Mary P.
• Beall, Patricia A.

Report Date:

1988-02-01

Pagination or Media Count:

31.0

Abstract:

This study was conducted to determine the effects on reproduction, if any, of oral administration to rats of a candidate wood preservative, zinc naphthenate. findings indicated that rats fed a diet of 0.5 zinc naphthenate experienced a significant weight loss. This weight loss had no effect on mating or viability of offspring over two generations of rats on study. Therefore, zinc naphthenate was not considered to be a reproductive hazard in rats under the conditions of this study. Recommendations provide for the use of appropriate personal protection when handling zinc naphthenate solutions.

Descriptors:

• *INGESTION(PHYSIOLOGY)
• HAZARDS
• RATS
• DIET
• WEIGHT REDUCTION
• ORAL INTAKE
• REPRODUCTION(PHYSIOLOGY)

Subject Categories:

• Genetic Engineering and Molecular Biology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE