Accession Number:

ADA235134

Title:

Proton Arc Doses to the Primate Head

Descriptive Note:

Final rept. 30 Nov 1989-30 Sep 1990

Corporate Author:

TEXAS A AND M RESEARCH FOUNDATION COLLEGE STATION

Personal Author(s):

Report Date:

1990-12-01

Pagination or Media Count:

21.0

Abstract:

The radiation dose distributions to the primate head are calculated for 10 MeV, 32 MeV, 55 MeV, and 110 MeV protons incident in the primate. Rotation of the primate in the fields is simulated by summing a 360-degree arc in 12 degree increments. Representative anatomy is determined by computerized tomography scans of a primate head phantom. Dose-volume histograms are used to compare the dose to the brain for each of the four irradiation techniques. Surface dose and depth dose calculations are made to evaluate the dosimetric effects to the primate eye. Estimates are made of the effects of irradiation with the primate eyes open versus closed. A focusing effect is described to explain the localized high doses seen with 32 MeV and 55 MeV proton exposures. Doses to the eye are calculated and tabulated by animal identification key for a series of irradiated primates. These calculations demonstrate significant departures from the dose predictions based on simple cylindrical phantoms, suggesting that careful review of the primate dosimetry must accompany any evaluation of radiation effects on these animals.

Subject Categories:

  • Radiobiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE