Accession Number:

ADA234814

Title:

Lyme Disease in South America?

Descriptive Note:

Journal article

Corporate Author:

NAVAL MEDICAL RESEARCH INST BETHESDA MD

Personal Author(s):

Report Date:

1991-01-01

Pagination or Media Count:

3.0

Abstract:

As a preliminary step in the determination of the presence or absence of Lyme borreliosis in Peru, a retrospective serum survey was conducted. Serum samples of a group of 216 individuals males or 10 years old, chosen as a high risk group due to their agricultural profession, were tested for the presence of antibodies to Borrelia burgdorferi antigen. For this survey, a commercially available ELISA kit Cambridge Bioscience, Worcester, MA, utilizing antigen-coated microdilution plates was used. This test kit was recently reviewed and compared to Western Blot analysis the sensitivity and specificity were 89 and 100, respectively. Of the 216 sera tested, 4, or nearly 2, were positive for antibody to B. burgdorferi positive sera were run a second time for reconfirmation. Due to the nature of a retrospective survey, limited clinical data were available on the positive patients. One of the four antibody-positive patients was acutely ill with hepatitis B and rapid plasma reagin-positive and weakly reactive on the fluorescent treponemal absorption test.

Subject Categories:

  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE