Final Report on Contract N00014-88-K-0059 (California University),
CALIFORNIA UNIV SAN FRANCISCO
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There is an abundant amount of evidence suggesting that catecholamines administered centrally can regulate adrenocorticotropin ACTH and vasopressin AVP release. Because there is a heavy catecholaminergic projection from the brainstem innervating the para-ventricular nucleus PVN of the hypothalamus, the nuclear region that regulates AVP and ACTH release from the pituitary it has been suggested that catecholaminergic regulation of ACTH and AVP may occur directly at this site. Also, these catecholaminergic cell groups are located in regions involved in the regulation of baroreflexes and the regulation of arterial blood pressure and heart rate during hemorrhage.
- Medicine and Medical Research