Accession Number:

ADA234671

Title:

Prophylactic and Treatment Drugs for Organophosphorus Poisoning

Descriptive Note:

Annual rept. 30 Sep 1988-29 Mar 1990

Corporate Author:

ASH STEVENS INC DETROIT MI

Report Date:

1990-08-01

Pagination or Media Count:

74.0

Abstract:

The program is directed at the design and synthesis of treatment and prophylactic drugs as potential defenses against organophosphorus poisoning. During the past year, 23 compounds were submitted three organophosphonates, eight carbamates, one organophosphinic acid, two sadium alkylthiosulfonates, thiosulfonates, thiotaurine, and homothiotaurine, cis-4-chlorobuten-1-o1 and 4- chlorobutanol, one alkylaryl disulfide, two chloroalkyaryl carboxylic acids, 1,3,5-tris-2-chloroethylbenzene and d8-thiodiglycol.

Subject Categories:

  • Pharmacology
  • Chemical, Biological and Radiological Warfare

Distribution Statement:

APPROVED FOR PUBLIC RELEASE