Prophylactic and Treatment Drugs for Organophosphorus Poisoning
Annual rept. 30 Sep 1988-29 Mar 1990
ASH STEVENS INC DETROIT MI
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The program is directed at the design and synthesis of treatment and prophylactic drugs as potential defenses against organophosphorus poisoning. During the past year, 23 compounds were submitted three organophosphonates, eight carbamates, one organophosphinic acid, two sadium alkylthiosulfonates, thiosulfonates, thiotaurine, and homothiotaurine, cis-4-chlorobuten-1-o1 and 4- chlorobutanol, one alkylaryl disulfide, two chloroalkyaryl carboxylic acids, 1,3,5-tris-2-chloroethylbenzene and d8-thiodiglycol.
- Chemical, Biological and Radiological Warfare