Accession Number:

ADA234135

Title:

Evaluation of Dried Storage of Platelets and RBC for Transfusion: Lyophilization and Other Dehydration Techniques

Descriptive Note:

Annual rept. no. 2, 1 Feb 1990-31 Jan 1991

Corporate Author:

EAST CAROLINA UNIV SCHOOL OF MEDICINE GREENVILLE NC

Report Date:

1991-01-31

Pagination or Media Count:

22.0

Abstract:

This project is based on the empirical development of processes whereby blood platelets and erythrocytes can be stabilized to withstand lyophilization for long-term dried storage as a transfusion resource for combat casualty care. The investigators bring together expertise in lyophilization techniques, blood banking practice, platelet physiology and liquid storage studies, and blood cell survival assessments. The second year of this grant was focused on three major efforts extensive evaluation of paraformaldehyde- stabilized platelets para-plts, development of new stabilization protocols KMnO4, etc., and application of new and existing stabilization protocols to RBC.

Subject Categories:

  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE